Chapter One
TUTORIAL IN BIOSTATISTICS
Multilevel modelling of medical data
Harvey Goldstein, William Browne and Jon Rasbash
Institute of Education; University of London; London; U.K.
SUMMARY
This tutorial presents an overview of multilevel or hierarchical data modelling and its applications in
medicine. A description of the basic model for nested data is given and it is shown how this can
be extended to fit flexible models for repeated measures data and more complex structures involving
cross-classifications and multiple membership patterns within the software package MLwiN. A variety
of response types are covered and both frequentist and Bayesian estimation methods are described.
Copyright (c) 2002 John Wiley & Sons, Ltd.
KEY WORDS: complex data structures; mixed model, multilevel model; random effects model;
repeated measures
1. SCOPE OF TUTORIAL
The tutoria ... read full excerpt from Tutorials in Biostatistics ebook
