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Home > Science & Nature > Life Sciences > Life Sciences - Biochemistry > The Ubiquitous Roles of Cytochrome P450 Proteins: Metal Ions in Life Sciences-eBook
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The Ubiquitous Roles of Cytochrome P450 Proteins: Metal Ions in Life Sciences
Helmut Sigel, Astrid Sigel and Roland K.O. Sigel, in close cooperation with John Wiley & Sons launch a new Series “Metal Ions in Life Sciences”.

There exists a whole range of books on Cytochromes P450, but none with the focus of this volume. This new volume in the Series concentrates on current hot topics in the area and tries to work out the underlying common developments.

As a result the reader will find a systematic account of new results in this exciting research area. The table of contents gives an idea on the wide span of chapters, starting with overviews and the presentation of specific systems, and ending with chapters on carbon-carbon bond cleavage by P450 sytems, drug metabolism as catalyzed by P450 systems, decomposition of xenobiotics by P450 enzymes and design and engineering of new P450 systems.

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Title of ebook: The Ubiquitous Roles of Cytochrome P450 Proteins: Metal Ions in Life Sciences
ISBN: 9780470028148
Publisher: John Wiley & Sons, Inc.
Internet download file size: 14013 kb
Pages: 678
Released online for download: 04-30-2007
Editor: Sigel, Astrid
Editor: Sigel, Helmut
Editor: Sigel, Roland K. O.

The Ubiquitous Roles of Cytochrome P450 Proteins

Metal Ions in Life Sciences

Chapter One

Diversities and Similarities in P450 Systems: An Introduction

Mary A. Schuler and Stephen G. Sligar

1. OXYGENASES: MEDIATORS OF BIOCHEMICAL DIVERSITY 2 2. P450 SUPERFAMILY: DIVERSITY AT THE SEQUENCE LEVEL 3 3. DIVERSITY OF P450 STRUCTURES: FOLDS AND CONFORMATIONS FOR FUNCTIONS 5 4. DIVERSITY IN P450 MECHANISMS 6 4.1. Diversity of Redox Partners 6 4.2. The Heme-Oxygen Catalytic Landscape 9 4.3. The Oxy and Peroxo Iron Intermediates 10 4.4. High-Valent Metal-Oxo Complexes ... read full excerpt from The Ubiquitous Roles of Cytochrome P450 Proteins: Metal Ions in Life Sciences ebook



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