Randomization in Clinical Trials: Theory and Practice ebook Rosenberger, William F., Lachin, John M. Diesel eBooks

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Home > Education > Mathematics > Randomization in Clinical Trials: Theory and Practice-eBook

Randomization in Clinical Trials: Theory and Practice

Rosenberger, William F., Lachin, John M.

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Randomization in Clinical Trials: Theory and Practice

A unique overview that melds the concepts of conditional probability and stochastic processes into real-life applications

The role of randomization techniques in clinical trials has become increasingly important. This comprehensive guide combines both the applied aspects of randomization in clinical trials with a probabilistic treatment of properties of randomization. Taking an unabashedly non-Bayesian and nonparametric approach to inference, the book focuses on the linear rank test under a randomization model, with added discussion on likelihood-based inference as it relates to sufficiency and ancillarity. Developments in stochastic processes and applied probability are also given where appropriate. Intuition is stressed over mathematics, but not without a clear development of the latter in the context of the former.

Providing a consolidated review of the field, the book includes relevant and practical discussions of:
* The benefits of randomization in terms of reduction of bias
* Randomization as a basis for inference
* Covariate-adaptive and response-adaptive randomization
* Current philosophies, controversies, and new developments

With ample problem sets, theoretical exercises, and short computer simulations using SAS, Randomization in Clinical Trials: Theory and Practice is equally useful as a standard textbook in biostatistics graduate programs as well as a reliable reference for biostatisticians in practice.

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Title of ebook: Randomization in Clinical Trials: Theory and Practice
ISBN: 9780471654070
Publisher: Wiley-Interscience
Internet download file size: 13220 kb
Pages: 288
Released online for download: 01-21-2005
Author of eBook: Rosenberger, William F.
Author of eBook: Lachin, John M.