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Home > Computers > Computers General & Other > Genomic Perl-eBook

Genomic Perl

Dwyer, Rex A.

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Genomic Perl

This introduction to computational molecular biology will help programmers and biologists learn the skills needed to start work in this important, expanding field. The author explains many of the basic computational problems and gives concise, working programs to solve them in the Perl programming language. With minimal prerequisites, the author explains the biological background for each problem, develops a model for the solution, then introduces the Perl concepts needed to implement the solution. The book covers pairwise and multiple sequence alignment, fast database searches for homologous sequences, protein motif identification, genome rearrangement, physical mapping, phylogeny reconstruction, satellite identification, sequence assembly, gene finding, and RNA secondary structure. The concrete examples and step-by-step approach make it easy to grasp the computational and statistical methods, including dynamic programming, branch-and-bound optimization, greedy methods, maximum likelihood methods, substitution matrices, BLAST searching, and Karlin-Altschul statistics. Perl code is provided on the accompanying CD.

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Title of ebook: Genomic Perl
ISBN: 9780511057069
Publisher: Cambridge University Press
Internet download file size: 1804 kb
Pages: 352
Released online for download: 02-19-1999
Author of eBook: Dwyer, Rex A.