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Home > Medical > Diseases > Staphylococci in Human Disease
Staphylococci in Human Disease
 
 
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Staphylococci in Human Disease
Staphylococci remain the most important cause of hospital-acquired infections in the U.S. and MRSA has become the most common cause of skin and soft tissue infection in many parts of the world.

There is now a much greater understanding of the physiology and evolution of the staphylococci and this new edition reflects the rapid advancements in knowledge about this pathogen and provides a comprehensive review from both clinical and basic science perspectives.

The first section addresses the basic biology of the staphylococci, their molecular genetics, host defenses and host evasion, virulence determinants, mechanisms of antibiotic resistance, and laboratory techniques. The second section deals with epidemiology, and the third section provides an overview of the varied clinical manifestations of human staphylococcal infections. The fourth section covers prevention and treatment of these often life-threatening infections.

Written by experts from around the globe, this book is essential reading for all clinicians and basic scientists studying the staphylococci.



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Title of ebook: Staphylococci in Human Disease
ISBN: 9781444308471
parent-ISBN: 9781405163323
Publisher: Wiley-Blackwell
Internet download file size: 6122 kb
Pages: 688
Published: 10-2009
Released online for download: 10-13-2009
Editor: Crossley, Kent
Editor: Jefferson, Kimberly
Editor: Archer, Gordon
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Staphylococci in Human Disease


Chapter One

The Biology of Staphylococci

Greg A. Somerville and Richard A. Proctor

Historical perspective of the isolation and characterization of the staphylococci

The staphylococci make up the family of Gram-positive cocci, Staphylococcaceae, which is in the order Bacillales. The term "staphylococcus" was synthesized from the Greek word staphyle, meaning bunch of grapes, for their ability to form microscopic grape-like clusters, and the term "coccus," meaning grain or berry. Staphylococcus aureus was one of the first bacterial pathogens identified, and causes a very broad range of infections including impetigo, folliculitis, superficial and deep skin abscesses, wound infections, osteomyelitis, suppurative arthritis, pneumonia, pleural emphysema, meningitis, septicemia and endocarditis, toxic shock syndrome, scalded skin syndrome, and food poisoning.

Koch first differentiated Gram-positive cocci in 1878 and recognized that different diseases such as abscesses correlated ... read full excerpt from Staphylococci in Human Disease ebook



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