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Sadana, Ajit Handbook of Biosensors and Biosensor Kinetics eBook

Handbook of Biosensors and Biosensor Kinetics

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Imprint: Elsevier Science

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Biosensors are essential to an ever-expanding range of applications, including healthcare; drug design; detection of biological, chemical, and toxic agents; environmental monitoring; biotechnology; aviation; physics; oceanography; and the protection of civilian and engineering infrastructures. This book, like the previous five books on biosensors by this author (and one by the co-author), addresses the neglected areas of analyte-receptor binding and dissociation kinetics occurring on biosensor surfaces.

Topics are covered in a comprehensive fashion, with homogeneous presentation for the benefit of the reader. The contributors address the economic aspects of biosensors and incorporate coverage of biosensor fabrication and nanobiosensors, among other topics. The comments, comparison, and discussion presented provides a better perspective of where the field of biosensors is heading.




Serves as a comprehensive resource on biosensor analysis
Examines timely topics such as biosensor fabrication and nanobiosensors
Covers economic aspects and medical applications (e.g., the role of analytes in controlling diabetes)

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Title of eBook: Handbook of Biosensors and Biosensor Kinetics
Release Date: 09-29-2010
Publisher: Elsevier Science

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Parent title Handbook of Biosensors and Biosensor...
Encrypted (DRM) Yes
SKU 9780080932859
File size 12350
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Handbook of Biosensors and Biosensor Kinetics


Chapter One

Introduction

Chapter Outline

1.1 Introduction 1 1.2 Biosensor Markets and Economics 9 1.3 Chapter Contents 11

1.1 Introduction

Biosensor applications have expanded considerably over the last few years after a modest beginning with the control application for the detection of glucose in the management of diabetes mellitus (DM). This is due to the ease of application of these biosensors to different areas of application. Some of the more recent areas of application include:

(a) Quantum dot biosensors for ultrasensitive multiplexed diagnostics (Berger, 2010).

(b) GE Healthcare have purchased Biacore™ and Microtal™ and combined the use of the SPR (surface plasmon resonance) biosensor with ITC (isothermal titration calorimetry) to provide orthogonal label-free determinations of affinity, binding kinetics, residence time, and enthalpic efficiency. They have also developed Bia2iTC software that compares outputs for both instruments (GE Healthcare, personal communication, 2010).

(c) Other interesting biosensor applications include (SPIE, Optics/Photonics in Security and Defence, 2006):

(1) Unmanned/unattended sensors and sensor networks (2) Technologies for optical countermeasures (3) Optically based biological and chemical detection for defence (4) Femtosecond phenomena and nonlinear optics (5) Optics and photons for counter-terrorism and crime-fighting

(d) Different sensing platforms have been integrated to achieve results unattainable by a single sensor. For example, electrochemical, mechan

...

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