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Quality of Life: The Assessment, Analysis and Interpretation of Patient-reported Outcomes
By: Peter Fayers , David MachineBook Publisher: John Wiley & Sons
Imprint: John Wiley & Sons, Ltd.
Format: Adobe Encrypted (DRM)
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Quality of life studies form an essential part of the evaluation of any treatment. Written by two authors who are well respected within this field, Quality of Life: The Assessment, Analysis and Interpretation of Patient-reported Outcomes, Second Edition lays down guidelines on assessing, analysing and interpreting quality of life data. The new edition of this standard book has been completely revised, updated and expanded to reflect many methodological developments emerged since the publication of the first edition. Covers the design of instruments, the practical aspects of implementing assessment, the analyses of the data, and the interpretation of the results Presents all essential information on Quality of Life Research in one comprehensive volume Explains the use of qualitative and quantitative methods, including the application of basic statistical methods Includes copious practical examples Fills a need in a rapidly growing area of interest New edition accommodates significant methodological developments, and includes chapters on computer adaptive testing and item banking, choosing an instrument, systematic reviews and meta analysis
This book is of interest for everyone involved in quality of life research, and it is applicable to medical and non-medical, statistical and non-statistical readers. It is of particular relevance for clinical and biomedical researchers within both the pharmaceutical industry and practitioners in the fields of cancer and other chronic diseases.
Reviews of the First Edition – Winner of the first prize in the Basis of Medicine Category of the BMA Medical Book Competition 2001:
“This book is highly recommended to clinicians who are actively involved in the planning, analysis and publication of QoL research.” CLINICAL ONCOLOGY
“This book is highly recommended reading.” QUALITY OF LIFE RESEARCH
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| Title of eBook: Quality of Life: The Assessment, Analysis and Interpretation of Patient-reported Outcomes | |
| Release Date: 05-29-2007 | |
| Publisher: John Wiley & Sons, Ltd. |
This eBook download is available in the following formats:
| Parent title | Quality of Life: The Assessment,... |
|---|---|
| Encrypted (DRM) | Yes |
| SKU | 9780470024515 |
| File size | 7157 |
| Security | n/a |
| Printing | Not allowed |
| Copying | Not allowed |
| Read aloud | No Sys requirements Download reader |
| Devices | Samsung Tablet, Apple Ipad & Iphone, Barnes & Noble Nook, Kobo eReader, Aluratek Libre, Iliad, Nokia, Blackberry, Hanlin |
| Note | Excellent navigation features are available via Adobe such as bookmarks and a quick access table of contents. Text search is easily accessible. An Adobe DRM-protected file is different than a pdf file in that it uses Adobe DRM (Digital Rights Management) technology, which authors and publishers use to protect their content from illegal online distribution and to set certain privileges such as restrictions on copying and printing. |
Quality of Life: The Assessment, Analysis and Interpretation of Patient-reported Outcomes
Chapter One
Introduction
Summary
A key methodology for the evaluation of therapies is the randomised controlled trial (RCT). These clinical trials have traditionally considered relatively objective clinical outcome measures, such as cure, biological response to treatment, or survival. More recently, investigators and patients alike have argued that subjective indicators should also be considered. These subjective indicators are often regarded as indicators of quality of life. They comprise a variety of measurement scales, such as emotional functioning (including anxiety and depression), physical functioning, social functioning, pain, fatigue, other symptoms and toxicity. A large number of questionnaires, or instruments, have been developed for quality of life assessment and have been used in a wide variety of circumstances. This book is concerned with the development, analysis and interpretation of data from these quality of life instruments.
1.1 Patient-reported outcomes
This book accepts a broad definition of quality of life, and discusses the design, application and use of single- and multi-item, subjective, measurement scales. This encompasses not just 'overall quality of life' but also the symptoms and side effects that may or may not reflect - or affect - quality of life. Some researchers prefer to emphasise that we are only interested in health aspects, as in health-related quality of life (HRQoL or HRQL), while others are now adopting patient-reported outcomes (PROs) as the description, because that term indicates interest in a whole host of outcomes, such as pain, fatigue, depression through to physical symptoms,
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