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Mecklenburg, Lars Hair Loss Disorders in Domestic Animals eBook

Hair Loss Disorders in Domestic Animals

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eBook Publisher: John Wiley & Sons
Imprint: Wiley-Blackwell

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Hair Loss Disorders in Domestic Animals is an in-depth reference on the pathomechanisms and clinical approaches of all skin diseases in domestic animals that have hair loss as the predominant clinical feature. It presents both basic and clinically-relevant knowledge on alopecic disease in animals. This text is a one-of-a-kind resource providing cutting-edge coverage of the physiology and pathology of hair follicles. Disease-specific chapters include: a detailed description of the disease entity, etiology, pathogenesis, clinical and histopathological diagnosis and treatment modalities.

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Title of eBook: Hair Loss Disorders in Domestic Animals
Release Date: 09-15-2009
Publisher: Wiley-Blackwell

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Parent title Hair Loss Disorders in Domestic Animals
Encrypted (DRM) Yes
SKU 9780813819341
File size 24748
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Copying Not allowed
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Hair Loss Disorders in Domestic Animals


Chapter One

Ontogeny of the hair follicle

Desmond J. Tobin

Both humans and domestic animals communicate significantly via their physical appearance, and the hair fiber-producing mini organ called the hair follicle accounts for much of the variation in domestic mammal phenotype. Although commonly dismissed as being of superficial importance, the hair follicle is truly one of the nature's most fascinating structures (Chuong 1998). Hair growth, one of the only two uniquely mammalian traits (the other is the mammary gland), serves several important functions. These include thermal insulation, camouflage, social and sexual communication, sensory perception, and protection against trauma, noxious insults, insects, and so on. These features have clearly facilitated evolutionary success in animals.

The hair follicle or, as it is known in humans, the "pilosebaceous unit" encapsulates all the important physiologic processes found in mammalia, including controlled cell growth and death, interactions between cells of different histologic type, cell differentiation and migration, and hormone responsitivity. Thus, the value of the hair follicle as a model for biological scientific research goes way beyond its scope for cutaneous biology or dermatology alone. Indeed, the recent and dramatic upturn in interest in hair follicle biology has focused principally on the pursuit of two of biology's holy grails: post-embryonic morphogenesis and control of cyclical tissue activity.

If one first considers the role of the skin, arguably our body's largest organ, as the mammal's sensor at the periphery (a veritable "brain

...

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