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Bilous, Rudy Handbook of Diabetes eBook

Handbook of Diabetes

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eBook Publisher: John Wiley & Sons
Imprint: Wiley-Blackwell

Format: ePub Encrypted (DRM)


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Over three editions the Handbook of Diabetes has built a reputation as an essential practical manual on the assessment and management of patients with diabetes. Previously written by Gareth Williams and John Pickup, the book has been completely revised by Rudy Bilous and Richard Donnelly to reflect recent changes in diabetes treatment and care. It contains information on the new IFCC units for measuring blood glucose and the latest drugs being used to combat diabetes, as well as alternative methods of insulin delivery.

The book has been fully updated and redesigned to make it even more user-friendly, and contains case histories, practice points, and landmark clinical trials highlighted in color in each chapter where appropriate. It also features an entirely new set of clinical photographs, and all 250 images from the book can be downloaded from the companion CD for use in presentations.

The Handbook of Diabetes is the ideal practical handbook for all health professionals with an interest in diabetes care.

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Title of eBook: Handbook of Diabetes
Release Date: 10-19-2010
Publisher: Wiley-Blackwell

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Parent title Handbook of Diabetes
Encrypted (DRM) Yes
SKU 9781444391367
File size 14688
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Handbook of Diabetes


Chapter One

Introduction to diabetes

KEY POINTS

Diabetes is common and its incidence is rising.

Type 2 diabetes is by far the most common accounting for 8595% of cases.

Complications in the microvasculature (eye, kidney and nerve) and the macrovasculature are responsible for considerable morbidity and excess mortality.

Diabetes mellitus is a condition of chronically elevated blood glucose concentrations which give rise to its main symptom of passing large quantities of sweet-tasting urine (diabetes from the Greek word meaning 'a siphon', as the body acts as a conduit for the excess fluid, and mellitus from the Greek and Latin for honey). The fundamental underlying abnormality is a net (relative or absent) deficiency of the hormone insulin. Insulin is essentially the only hormone that can lower blood glucose.

There are two categories of diabetes: type 1 is caused by an autoimmune destruction of the insulin-producing cell of the islets of Langerhans in the pancreas (absolute deficiency); and type 2 is a result of both impaired insulin secretion and resistance to its action - often secondary to obesity (relative deficiency).

The precise level of blood glucose that defines diabetes has been revised several times and is covered in more detail in Chapter 3. Diabetes is common and is becoming more common. Age-adjusted prevalence is set to rise from 5.9% to 7.1% (246-380 million) worldwide in the 20-79 year age group, a 55% increase (Figure 1.1). The relative proportions of type 1 to type 2 vary from 15:85 for Western populations to 5:95 in developing countries.

It is t

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