As a result of widespread financial pressures, U.S. research universities increasingly stress the pursuit of funding beyond that available from government grants and contracts. Concomitantly, recent legal changes have encouraged universities to develop closer ties to the private business sector. This book represents the most thorough review ever undertaken of a major collaboration between industry and academe. A professional evaluation team obtained authorization for unprecedented access to those associated with the landmark $25 million contract entered into by the Plant and Microbial Biology Department at the University of California, Berkeley, and the Novartis Agricultural Discovery Institute, a subsidiary of Novartis, an international pharmaceutical and agribusiness conglomerate. This model study presents the inside story of the partnership itself, places it in the context of contemporary university-industry relationships, and provides a larger theoretical framework for evaluating such collaborations in the future.